Association between Polymorphisms of the IL-23R Gene and Allergic Rhinitis in a Chinese Han Population
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چکیده
منابع مشابه
Association between Polymorphisms of the IL-23R Gene and Allergic Rhinitis in a Chinese Han Population
OBJECTIVE Polymorphism of the interleukin-23 receptor gene corresponds with susceptibility to several immune-related diseases. For the terminal differentiation of IL-17-producing effector T-helper cells in vivo, the interleukin-23 receptor gene is of vital importance. As shown recently, Th17 cells probably have a great influence on the pathogenesis of allergic airway diseases. Our intention was...
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tumor necrosis factor alpha-inducible protein 3 (tnfaip3) gene polymorphisms have been reported to be associated with the susceptibility to several immune-related diseases. here we investigated the effect of tnfaip3 gene polymorphisms on the risk of allergic rhinitis (ar) in a chinese han population. the case-control study included 540 ar patients and 524 healthy controls. genotyping for tnfaip...
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BACKGROUND TIM-1, a member of the T cell immunoglobulin and mucin (TIM) domain family, is involved in T-cell differentiation and has been implicated in allergic diseases. An association between TIM-1 and allergic rhinitis, however, has not been established. OBJECTIVE To investigate whether TIM-1 gene polymorphisms were associated with allergic rhinitis in a Han Chinese population. METHODS T...
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BACKGROUND Heredity and environmental exposures may contribute to a predisposition to allergic rhinitis (AR). Autoimmunity may also involve into this pathologic process. FCRL3 (Fc receptor-like 3 gene), a novel immunoregulatory gene, has recently been reported to play a role in autoimmune diseases. OBJECTIVE This study was performed to evaluate the potential association of FCRL3 polymorphisms...
متن کاملAssociation Pattern of Interleukin-1 Receptor-Associated Kinase-4 Gene Polymorphisms with Allergic Rhinitis in a Han Chinese Population
OBJECTIVE Interleukin-1 receptor-associated kinase-4 (IRAK-4) encodes a kinase that is essential for NF-kB activation in Toll-like receptor and T-cell receptor signaling pathways, indicating a possible crosstalk between innate and acquired immunities. We attempted to determine whether the polymorphisms in the Interleukin-1 receptor-associated kinase-4 (IRAK-4) gene are associated with allergic ...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2013
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0063858